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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5680989f2c89a0465c316b5ca3a2170647ebe211869aae8bca1cec3101bacb78' 
  AND token = 'ZtQKerEAKZQ96LXJVqSD4R+GQWpp+oSSRFgwccDn1yY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}