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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c09e7fc4347a101d7d551744f79e41eab752965d9983735df766926533a1f378' 
  AND token = 'HhOfb7GEnmiYNExRbixetLBPIMN2vXnH7focvk8DOWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}