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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c00158ade00ae69edf990b7c0ef16375acf98d5756ff31f17e8c8781cd31a99' 
  AND token = 'DQy5uhP4E7sSoyOH9zo21lCh/FF4LTNRqUSsQHlskNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}