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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70bdb726b5ab520ae99e053d20049113fcbd19bdb6c03e93778577b7ce74c5ae' 
  AND token = 'IZT9l77CPGsg4iioDersFeYK7qbXOw8NfDX5G1Ln4Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}