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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b157cd5ed81e19a9f9351a5ee1e5b54ac521371b5b1c0e95edcd110f757f98a6' 
  AND token = '+m/mNX66600N3MdTR8AnKB2vXX3gd888Jc2gxFeYn4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}