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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea03053d97c0c02b528f66f45fdcd6435cd09dfb272f6a852545549becfcf9a' 
  AND token = 'jEo7slp4XuFLr+n/iWJ8yAkU5WEqQk2t0rqVTr/aGFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}