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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29459752e0ddc2767cb10b87b27f5e7b36eb73f31f67e92b58f36092893aa210' 
  AND token = 'S54crBbihuqIKpD5iiOJfqfhtA//GVN4OoF1LaaAdeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}