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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f817846847a8418c18dd26b9b4d3d726914a0ba16541b5db083b2b93e09103' 
  AND token = 'qe+cYA8vJ6dCS39qSNktneJ+WVAhQ6hAYOIhZVU0krc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}