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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dae80bb292d0b286d2f7a632691fafb87a5ae1b4e59c3e04344ee2ffab627d8' 
  AND token = 'Py1KzOjs5CKwt/gj5MhrS6xqKF44j5YS5MCwM4KkUhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}