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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8276421c57a3a563155146772cd16af1056fcc1afa84d2838ed89d79781a07' 
  AND token = 'sDaupF4pXpjlxS3uE7b2R8lYj3E1HCrcQS3D9aMDhms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}