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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24810145f81f67565b022c2c8b1324b85381fa9994e1c36fe864789c466cb1dd' 
  AND token = 'PC0Z4odD6gXhiEDa+A/wxFtDuQue9njiyqCsn0H47kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}