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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1009a89f0ee491aa87c018bc08063adb97f0cf6fda6bd1961d7765968ec1790b' 
  AND token = 'UOStZoiPS217PSMgRRSaOzRItOECc3ygpqT1DUZM9XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}