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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b71e242c1fa12487eb60a9f18d422bbb8ffecce064282253a65ec0797d68b3' 
  AND token = 'W0LtkADpTkWPEDsG8XAAnKVaD1KEv4bFtIcNJwfzEeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}