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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e6c4d23f71843784b921b3ee3694b3a4fbd0e694d8643a0481adc03b855fe27' 
  AND token = 'uzkggP96XAka9zsQvfsb6qARMweeLIot3uXeWYrpojA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}