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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '663cdcc32a0d2d8cee5a034fecebbe15a19774126f201a1918cde7d2c2d4de5a' 
  AND token = 'bbS2NMq6IP8+GORk1WBZ5TpY1JDPNa7RbYEs5ZCpx2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}