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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '885cb6372e38901509ade75ee51ce407c44770b183d33c38d372c173c5401082' 
  AND token = 'dAQXxn6uK8/LMRyGuEO9jb+j0VCY3ZYlV0z1pHF+hyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}