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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '407844aa230e1393a9478daba2a4c0dcc3ad19e582c2bf02e21bd1d23ceea2f0' 
  AND token = 'MERbECg/Wv/7yMqwO4LI4WO/+pcgIsCQ3UP2OQiNRhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}