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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '444fad82d105478970331a73b96cf844fd4334828114b496c43fdf1362054ca0' 
  AND token = 'avArlJo78K0vnS3lh2zTLz7wdTCF8Cl5MBqzfNXP8dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}