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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97667f8b77d30d2e2c7c9113dce7d0e8e5daa5635d2936d2eee9abc6fa396392' 
  AND token = '0s0nW+zZeFF+Zv/q/pJxxH5fMdEbpp+ujvIGvM4HrHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}