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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b14a449986f7f8fb6d0d9672367b62b069b4fe482dd6f1f2fb01ec2aa327b3' 
  AND token = '6HxLJW4oPhDfDd6JQwjQDb8/uv2pZd0Lv/1sFLDxKak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}