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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb154383564970960d931093a5f5495460e8df90334f77a5a5b7a381b18f3caf' 
  AND token = 'WRQDI899H4p6abU7OKV2/oA55lQlcVls4zHlm9PhvMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}