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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7042fd1686167eef2ba8ba054d5cc3d21ff0258c38fd0c4089e17bb22ca067' 
  AND token = 'NzeRrYTf+mH2J1sy6yHajPnP1xCLmL7dHb2dP2F2TCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}