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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a309e15ab56072913dc68165a1395d3f50493b7066ee31de1aa40fcaa3eba8' 
  AND token = '+5OrjtNuDbys//9H2SYcrikaMLUGfVQeNnY3fIXntR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}