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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26426c59ce69dde756822c5da75a6d7a879acb3712328abd108c69de4bfb320a' 
  AND token = 'ESWXLDQWXuZJ+h9CpO49tRY7B/dabXMuTjMQ1YCj0FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}