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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b7d741b48e22f2534cee543050e6a3fac9346e34394e0f00cc56eca5280b3f4' 
  AND token = 'Qimzn7Ff7bRqTSNOTVdUDowO8qSZ6JFl3FsbrTd3t4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}