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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48050c90975f2f5412bbac702e5d746ec5ae93ad500cca27ac960f938b59a4f2' 
  AND token = 'Bh8+eU9ywarEk7ZmdKiqyIBOX4+a5GAGt4DnjsuMB3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}