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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149dbc2e1bfb1cbac99e769099dd6a63db7f3876be4b9320324765f8473fbb70' 
  AND token = 'R+tcr8LkcmDSr8u1whOhzAszBxX+H4kGGMuF0UXwetI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}