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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb3ef5dcc3157d68aed50ae55d02cedd5868e4b2475c3e2bbdca53b5b68e25f' 
  AND token = 'Z/82j+s9AupjPY7Wmnw5uBGd8AbXQYlTxP8IYteB1NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}