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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e150b5d602ac11f262b94caedf77a1f9a9d75697b4a6c67c63139f430f3163' 
  AND token = 'FlHHFb52FKOnfUqGqzxL5QKqY3XrfXmaZcp690NDmpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}