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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fe24919412994168d5df8d892cdd37be74761e0c4592c3806b347bbaf45485' 
  AND token = 'sf1hWLn31Vb25orTNgckXA2gdAcIxPNBhNYepBWvOQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}