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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1250d2366fc9f9618b241e8c0847313275c8ea2f9d2169bea240fc38da8ee8' 
  AND token = 'K8AMkd03fNvjLyGj6uCx8mKBRom4EFGn9kXVkluVMs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}