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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0dd806a5aefb1804663b38696c21645fdd2bef42dd20d5d94a7d8174c9e090' 
  AND token = 'IB3r7Tr5kVhSfPLm4oZ/8i9b3D88lPKuOYuWQ141IYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}