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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b811816918f5a3f450eef7804de43c54c4226a946f7ae0aab8cd3f0f6620def' 
  AND token = '7p12ABnL/fJ5aB82zF6JR5WHlVMWjLtJMOARa/mk3O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}