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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557c9553fa93ddd2f5fabe5094ff08980e90fb5e382d95a4909284e21a2eb269' 
  AND token = 'cqny1GzIAAv9Re3uvjqXUoqJp9lg+re6513Xz0CJSGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}