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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d81adeb527f76a34f7b57b7827c20f6ff2d1cb898f9eb3cab018a39e3247233' 
  AND token = 'fp3JDo6knYmCNCAadj55o2BJTnVFdIuuHI+4Jg2WosY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}