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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d2371ac620df98b3b9a12bdea052c9f8f54926c51b3a12cf5fb5f4ea0fdf21d' 
  AND token = 'BluBA0NzCiqfWkOuy7/zfAMTQMmt14S/NiYdEMtGOPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}