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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9868690d6017fd7ed78c71c4eb6262d2aa95e516a54104eac0abe5b26352a9' 
  AND token = 'J0ShIck+aiVDh2AZL1p/Chcpjfodo9k9V7ji2qCwDEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}