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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bbc64893cf15f807c1448635be7efc1a5bac1f1b92a04709840a2f91ff99d6d' 
  AND token = 'nqYjmkbK0N0NgNl8aIS+9iTDhQnrE73mRid8NwAAHRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}