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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86726f4adfa94b05bc7fde9db2df72d1b6ef18e04ea49f8e7d99d4a5ed4bee99' 
  AND token = '1kK/4+DaL4xUcCn2cdhWrroCsR1cZTkBkDUz2Lbf1DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}