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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356e9013a609378909c49bf293ee4387eb2872f82a7f73428c7476c9477b37b5' 
  AND token = 'b+oO7SwGyuipfRcHoWvELLwZsGEmIiDV+1fH02gqCuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}