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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789bee134ebb22353dfe60f73615779d94451dd3677439763365158d55932df5' 
  AND token = 'YO0e/TRhXDLRZwNbeUx3+R9Xea4vpT0qFcDsF673PGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}