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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '405d79f51b69540084030d2891c36029c00868fd554e65f2bc337a28d21b17cc' 
  AND token = '7K+wiMeTGvEAO6dp+mzsfkHlEkQ0ThIy/Odz6R1GY7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}