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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168b67cde4a90dc37364b8097cac28644273bb54919f42fb02a5b437f9ee8e80' 
  AND token = 'xBtfJMsZKbYfuVE0t5bmaiD0vOOWnKvjW7XA7S7chcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}