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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e501e20db450fb6c87e220846cbc9d1efc1a7d7c7790a7641007ef618c5136a9' 
  AND token = 'i1Ppti76XmL4Z7hHqmRUzMzAU0x4wB+KKBV+z208Jyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}