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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1241b1c171a9c707c5d3ca861fad8c10bd83c7be5fabee63401b330f75ce32f2' 
  AND token = 'oG0tRAEChb1geBY5VTTjxfKS1Kq8HZiNiUDuJxDomPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}