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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e32c42aab582427a2a8bda932b45cebd34570c9b3a7a2e75f669dbf5fefc8881' 
  AND token = 'rOrHsI4j+lcD7Wdml8d3XoRH64ygUlsgKCGUGoNziXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}