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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c5ffbda6c8108b909b639873890c7fa3a8466b444a0f819e04d0bb695a878e1' 
  AND token = 'm9BCH78enbYUgf0IuNW0LlV0Z4zrRFaKl4/e5aT2hVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}