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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae05c0733a194251d7bbcc99f0dec882b9486b3492514d96ffda5efd886fce1' 
  AND token = 'aiCIic/BS/gS1EM6o1RM1gAGo1oE0XhP1oma2EVimaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}