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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad16bc6b417d2f6df259b3c41d652905f3971051813b48a72eb0448d9dc0a830' 
  AND token = 'VCIwMFw2XbqOF36oTk1wED9oDHQLRXviI75j3EwMC/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}