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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49b5f9f57a3a94c0bc76f4459d9db064514b248bc2eea09310c171032ed5ce6' 
  AND token = 'g17XioNRzVrmCKHMLZiF3rBupbl3jBdD86xsY81AJao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}